Laboratory of Biochemistry
and Biotechnology

The main scientific research field - design of mediums for microbial growth in  biotechnology, medicine and pharmacy .

Staff:

Head of Department Osolodchenko Tenyana P.

Publications for 2013-2015
Total number of publications is 114, among them 5 patents, 1 methodical recommendations, 2 аpplications for utility models, 1 аpplications for invention, 36 articles in scientific magazines and collections, 69 thesises of reports at scientific conferences.

The basic publications:
The methodical recommendations:
Calculation methods of integrated performance antimicrobial activity of antibacterial drugs / life .: Boiko M. Zaitsev AI, old SI, Osolodchenko TP, Kazmirchuk V. B V. Petrov FLP, Kharkov , 2015. - 29 p. - 500 pr.

The patents:
1.    Declaratory patent on useful model A method for producing fermentolyzat nutritional foundations of the current molasses for culturing microorganisms [Text] / EV Menkus, S., Ponomarenko, TP Osolodchenko T. In Luk'yanekno, AV port, LG . Shtyker // number 98199 UA, S12N 1/20 (2006.01) on 27. 04. 2015, Bul number 8, the application number 2014 10 236 from 18.09.2014.
2.    Declaratory patent on useful model A method for producing fermentolyzat nutritional bases of grain bards for culturing microorganisms [Text] / TP Osolodchenko, SV Polnomarenko, A. Litvinenko, T. In Luk'yanekno, Menkus OV, OV Port, LG Shtyker number 97598 UA, S12N 1/20 (2006.01) on 25. 03. 2015, Bul number 6, application number 10 237 2014 from 18.09.2014.
3.    Declaratory patent on useful model A process for preparing nutritious basics of molasses molasses for culturing microorganisms [Text] / S. Ponomarenko, TP Osolodchenko T. In Luk'yanekno, Menkus AV, AV port, DL Wolanska , A. farmhand number 98706 UA, S12N 1/20 (2006.01) Eid 12. 05. 2015, Bul number 9, application number 10238 2014 from 18.09.2014.
4.    Declaratory patent on useful model A method for producing fermentolyzat nutritional foundations of barley grains for culturing microorganisms [Text] / TP Osolodchenko, S. Ponomarenko, T. In Luk'yanekno, Menkus AV, AV port, OA Litvinenko, N. Zavada // number 99419 UA, S12N 1/20 (2006.01) on 10. 06. 2015, Bul number 11, the application number 2014 10 235 from 09.18.2014.
5.    Declaratory patent on useful model A process for preparing nutritious basics of barley grains for culturing microorganisms [Text] / S. Ponomarenko, TP Osolodchenko T. In Luk'yanekno, Menkus AV, AV port, AA Litvinenko , I. Zavada number 99420 UA, S12N 1/20 (2006.01) on 10. 06. 2015, Bul number 11, the application number 2014 10239 of 18.9.2014.
6.    Аpplication for utility model Culture media for the release of lactic acid bacteria capable of degradation of oxalate [Text] / TP Osolodchenko, S. Ponomarenko, AV port, Krestetska SL, DL Wolanska, LG Shtyker. // U application number 2015 11982 of 12/03/2015.
7.    Аpplication for utility model Growth media for the detection of staphylococcus "/ Ponomarenko SV, Osolodchenko TP, AV port, Krestetska SL, Pivnenko SY, Antusheva TI Pirtskhalava TV - Appl. u2015 09638 05/10/2015.
8.    Аpplication for invention The use of 2-aminoacetic acid as a means of antimicrobial action "/ Komisarenko A., M. Golik, Osolodchenko T. P. - appl. u 2016 00825 02.02.2016 p.
The articles:
1.    Boyko, N. N. Screening of antimicrobial activity of ethanolic extracts from raw materials containing alkaloids [Text] / N. N. Boyko, A. I. Zaytsev, T. P. Osolodchenko // Journal of Chemical and Pharmoceutical Research. – 2015. – Vol. 7 (5). – P. 160-166. ISSN 0975-7384 CODEN (USA)$ JCPRC5
2.    Structure and species composition of community-acquired infections of different localizations [Electronic resource] / T. Osolodchenko, I. Andreieva , T. Lukyanenko, I. Ryabova, O. Batrak // Annals Mechnicov Institute. - 2015. - № 3. - P. 20. - Access:http://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
3.    The test results of sensitivity to antibacterial agents in Staphylococcus spp [Electronic resource] / T. Osolodchenko, I. Andreieva, N. Zavada, O. Batrak, T. Lukyanenko // Annals Mechnicov Institute. - 2015. - № 3. - P. 21. - Access: http://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
4.    The range and level of antibiotic resistance in P. aeruginosa clinical isolates [Electronic resource] / T. Osolodchenko, I. Andreieva, I. Ryabova, N. Zavada, L. Shtyker // Annals Mechnicov Institute. - 2015. - № 3. - P. 32. - Access: : http://www.imiamn.org.ua/journal/3_2015/pdf/14.pdf
5.    Study of аntimicrobial аctivity of medications for wound treatment [Text] / Boyko N. Nick, Zaytsev І. Alexander, Osolodchenko P. Тatyana, Melnik L. Аnatoly, Nevmerzhitskiy V.Vitaliy, Volkov О. Тaras and Kazmirchuk V. Victor // Journal of Pharmacy and Pharmacology. – 2015. – Vol. 3. – N. 7 (20). – P. 350-355.
6.    S. V. Vlasov Synthesis and the antimicrobial activity  of 1-alkyl-5-methyl-3-phenyl-6-(5-phenyl-1,3,4-oxadiazol-2-yl) thieno[3,2-d] pyrimidine-2,4(1H,3H)-diones [Text] /  S. V. Vlasov, T. P. Osolodchenko,  S. M. Kovalenko, V. P. Chernykh, Journal of Organic and Pharmaceutical Chemical  N 1 (49) - 2015.- Vol. 13.- P 20-24.
7.    Synthesis and study of  the antimicrobial activity  of 3-amino-5-meyhyl-2-(alkylthio)-4-oxo-N-aryl-3,4-dihydrothieno[2,3-d] pyrimidine-6-carboxamides [Text] /  S. V. Vlasov,   S. M. Kovalenko, T. P. Osolodchenko, V. P. Chernykh. Ж. «News of pharmacy» - Bulletin farmatsiyi.- section analysis and synthesis of biologically active rechovyn.- number 1.- T. 81, 2015.- Р.6-10.
8.    The effect of substituents in the molecules of N-,R-alkyl amines on some gram-positive strains of microorganism [Text] /   M.Yu. Golik, N. A. Komissarenko, S. G. Leonova, T. P. Osolodchenko. Ж. «News of pharmacy» - Journal of Pharmacy.-.- № 2.- T. 82, 2015.- Р.66-69.

The main research projects of the laboratory:
1.NAMN 113/2013 "Study of the role of microorganisms distal intestinal oxalate in maintaining homeostasis"
2. NAMN 122/2014 "Development of antibiotic resistance in microorganisms inhibitors"
3. NAMN 130/2016 "Study of the biological effects of relativistic electrons flow"