The laboratory of respiratory infections prevention

 

 

Head Sc.D. in Medicine, professor Eugeny Babych

 

 

 

Research workers:

Irina V. Yelyseyeva - the leading research worker, Ph.D. in Medicine

Vladimir I. Belozersky the leading research worker, Ph.D. in Medicine

 

Larisa A. Zhdamarova - the leading research worker, Ph.D. in Medicine

 
Tetyana A. Chausovska - the leading researcher, Ph.D. in Medicine


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Olena Yu. Isaenko - the senior researcher, Ph.D. in Medicine

 

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Svitlana A. Kolpak - the junior researcher

 

Publications for 2013-2015

Total number of publications is 53, including 3 patents, 23 articles in scientific journals, 27 thesises of reports at scientific conferences.

 

The main publications:

 

The patents:

1.      Patent of Ukraine for Utility Model 86891 UA, IPC: A61K 35/66, A61K 35/00 The Method for Bacterial Diphtheria Antigen Obtaining / E. M. Babych, I. V. Yelyseyeva, V. I. Belozersky, L. A. Zhdamarova, O. Yu. Isaenko, I. V. Bobireva, T.V. Gorbach ; proprietor SE I. Mechnikov Institute of Microbiology and Immunology of NAMS of Ukraine Appl. u 2013 097794; Filing Date 05.07.2010; Date of Publication 06.08.2013; Bulletin. 1.

2.      Patent of Ukraine for Utility Model 80581 UA, IPC: G01N 33/48, G01N 33/483 Method for Control of Diphtheria Toxin Detoxification / E. M. Babych, Posokchov E.O., S. V. Kalinichenko, T. A. Ryzhkova, N. I. Sklyar, T. I. Antusheva, V. I. Belozersky, V.O. Eglit ; proprietor SE I. Mechnikov Institute of Microbiology and Immunology of NAMS of Ukraine Appl. u 2012 12005; Filing Date 18.10.2012; Date of Publication 10.06.2013; Bulletin. 11

3.      Patent of Ukraine for Utility Model 82743 UA, IPC: 61 31/00 Antimicrobial composition for inhibition of Pseudomonas aeruginosa biofilm formation / Yu. V. Lisnyak, N. I. Sklyar, V.V. Sarkis-Ivanova, S. V. Kalinichenko, V. I. Belozersky, M.B. Davidenko ; proprietor SE I. Mechnikov Institute of Microbiology and Immunology of NAMS of Ukraine Appl. u 2013 00448; Filing Date 14.01.2013; Date of Publication 12.08.2013; Bulletin. 15.

 

The articles:

  1. Fluorometry application for investigation of diphtheria toxin detoxification process [Text] / T. I. Antusheva, S. V. Kalinichenko, E. M. Babych, T. A. Ryzhkova, E.O Posokchov // Herald of biological and medical problems. 2013. V.3 (98), 1. P. 177-180.
  2. Study of influence of previous oral application of diphtheria antigenic preparations on rabbit allergic reaction forming after skin test [Electronic recourse] / Yelyseyeva I. V., Babych E. M., Zhdamarova L. A., Belozersky V. I., Bobireva I.V. // Annals of Mechnikov Institute. 2013. - 1. .40-43. Access mode.: http://www.imiamn.org.ua/journal.htm
  3. Influence of previous oral application of pertussis antigenic preparations on rabbit allergic reaction forming after skin test [Electronic recourse] / Yelyseyeva I. V., Babych E. M., Zhdamarova L. A., Belozersky V. I., Isayenko O. Yu. Bobireva I.V. // Annals of Mechnikov Institute. 2013. - 2. .51-57. Access mode.: http://www.imiamn.org.ua/journal.htm
  4. The modern state of development and application of probiotics, prebiotics and synbiotics [Electronic recourse] / Kalinichenko S.V., Babych E.M., Ryzhkova T.A., Maslii I.G., Korotkykh O.O., Danilina S.S., Solianik O.G., Shykova O.A., Sklyar N.I., Tkach L.N., Balak A. K., Nemkova S.M., Desiatnikova O.V. // Annals of Mechnikov Institute. 2013. - 3. .5-12. Access mode.: http://www.imiamn.org.ua/journal.htm
  5. The influence of ultrasound and millimeter waves on aghesive properties of C.diphtheriae [Text] / T. I. Antusheva, E. M. Babych, S. V. Kalinichenko, T.A. Ryzhkova, N. I. Sklyar, O.I. Kovalenko // Advances in current natural sciences. 2014. - 3. . 48-52. ISSN 1681-7494.
  6. The role of probiotics in human microecology [Electronic recourse] / Chepurnaya M.N., Babych E.M. // Annals of Mechnikov Institute. 2014. - 1. .5-9. Access mode.: http://www.imiamn.org.ua/journal.htm
  7. The study of the biological properties of probiotic Lactobacillus spp. strains under aerobic and microaerophilic cultivation conditions [Electronic recourse] / Babych E.M., Kalinichenko S.V., Korotkykh O.O., Ryzhkova T.A., Sklyar N.I., Maslii I.G., Balak A. K., Shkodovska N. Yu., Bagacha M. B. // Annals of Mechnikov Institute. 2014. - 1. .33-37. Access mode.: http://www.imiamn.org.ua/journal.htm
  8. Anti-adhesive therapies as a contemporary means to fight infectious diseases and adherence factors of Corynebacteria diphtheriae [Electronic recourse] / Yelyseyeva I. V., Babych E. M., Zhdamarova L. A., Belozersky V. I., Isayenko O. Yu., Kolpak S. A. // Annals of Mechnikov Institute. 2014. - 2. .7-19. Access mode.: http://www.imiamn.org.ua/journal.htm
  9. The peculiarities of antagonistic activity of Lactobacillus strains (isolated from different econiches and probiotics) under cultivation conditions different by gas composition [Electronic recourse] / Ryzhkova T.A., Kalinichenko S.V., Babych E.M., Sklyar N.I., Khvorostiana V.O., Shkodovska N. Yu., Kutsina O.M., Bagacha M. B. Annals of Mechnikov Institute. 2014. - 2. .64-69. Access mode.: http://www.imiamn.org.ua/journal.htm
  10. Biophysical characterization of the impact of electromagnetic and ultrasonic waves on biological objects [Electronic recourse] / Kalinichenko S.V., Antusheva T.I., Korotkykh O.O., Babych E.M. Kivva F.V., Kovaneko O.I., Ryzhkova T.A., Balak A.K. // Annals of Mechnikov Institute. 2015. - 3. .25-26. Access mode.: http://www.imiamn.org.ua/journal.htm
  11. Chromatographic analysis of exometabolites of Lactobacillus plantarum, obtained in different conditions of the gas composition of the atmosphere of cultivation and after influence of physical factors [Text] / Kalinichenko S.V., Korotkykh O.O., Babych E.M. Kivva F.V., Kovaneko O.I. // Herald of biological and medical problems. 2015. V.2 (123), 3. P. 283-289.
  1. Modern achievements in anti-idiotypic and synthetic peptide vaccines development / Isayenko O.Yu., E. M. Babych, I. V. Yelyseyeva, L. A. Zhdamarova, V. I. Belozersky, S. A. Kolpak // Bulletin of Bashkir University.   2015. 3. P.33-48.
  2. Study of Effects of Diphtheria Bacterial Antigenic Preparation Obtained by Means of Electromagnetic Radiation of Ultrahigh Frequency on the Formation of Humoral Antitoxic Immunity and Colonization Resistance in Experimental Animals [Text] / I. V. Yelyseyeva, E. M. Babych, L. A. Zhdamarova, V. I. Belozersky, S. A. Kolpak, A. K. Balak // Herald of biological and medical problems. 2015. Issue.3, V.2 (93). P. 277-282.
  3. Anti-adgesive strategy in complex antidiphtherial vaccines development as a perspective measure of C.diphtheriae circulation decrease among population [Text] / I. V. Yelyseyeva, E. M. Babych, L. A. Zhdamarova, V. I. Belozersky, Isayenko O.Yu., S. A. Kolpak // Russian journal of childrens infections.   2015. 3. P. 30-33.
  4. New Generation Vaccines / Isayenko O.Yu., E. M. Babych, I. V. Yelyseyeva, L. A. Zhdamarova, V. I. Belozersky, S. A. Kolpak // Bulletin of the Smolensk State Medical Academy. 2015. V. 14. 2.  P. 50-58.

 

 

The main research projects of the laboratory:

 

  1. AMS 100/2011 Increasing of safety and efficacy of diphtheria and pertussis vaccinal prevention by means of oral vaccination with subsequent parenteral vaccination
  2. NAMS 120/2014 Study of diphtheria toxoid combined with C. diphtheria surface antigens immunogenicity and double-testing methods of their safety
  3. NAMS 111/2013 Biological bases for synbiotic complexes development using electromagnetic and ultrasonic waves
  4. NAMS 129/2016 The research of biological and physicochemical prerequisites for development of antidiphtheritic preparations on the basis of probiotic strains  metabolites